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2005, Volume 21, Number 1-2, Page(s) 008-010     
[ Abstract (Turkish) ] [ PDF ] [ Similar Articles ]
E-CADHERIN AND Ki-67 EXPRESSION IN COLORECTAL CARCINOMAS AND THEIR RELATIONSHIP WITH STAGE, HISTOLOGICAL SUBTYPE AND GRADE
Mehmet KEFELİ, Filiz KARAGÖZ, Sancar BARIŞ, Levent YILDIZ, Oğuz AYDIN, Bedri KANDEMİR
Ondokuz Mayıs Üniversitesi Tıp Fakültesi, Patoloji Anabilim Dalı, Samsun
Keywords: Colorectal carcinoma, adenocarcinoma, mucinous carcinoma, E-cadherin, Ki-67

In this study, tissue slides from 102 colorectal resection specimens examined between 1998-2002 in the Department of Pathology, Faculty of Medicine, Ondokuz Mayis University were retrospectively reevaluated. E-cadherin and Ki-67 expression were demonstrated immunohistochemically and relationship of E-cadherin and Ki-67 expression with differentiation, histological subtype and stage were investigated. E-cadherin expression was seen in 89 of 102 (87%) colorectal adenocarcinomas and mucinous carcinomas. Twentythree cases were (+), 32 cases (++) and 34 cases (+++). Ki-67 expression was seen in 86 cases (84%) with a mean value of 16.7%. There was a relationship between E-cadherin and Ki-67 expression and tumor differentiation. However no relationship between E-cadherin and Ki-67 index with tumor stage and histological subtype was found.

[ Abstarct (Turkish) ] [ PDF ] [ Similar Articles ]