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2011, Volume 27, Number 1, Page(s) 068-072
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DOI: 10.5146/tjpath.2010.01048 |
Pulmonary Carcinosarcoma: A Case Report |
Sevda SERT BEKTAŞ1, Sema BİRCAN1, Ahmet BİRCAN2, Mehmet SIRMALI3, Sedat GÜNEŞ3, Kemal K. BOZKURT1, Tuba DEVRİM1 |
1Department of Pathology, Süleyman Demirel University, Faculty of Medicine, ISPARTA, TURKEY 2Department of Pulmonary Diseases, Süleyman Demirel University, Faculty of Medicine, ISPARTA, TURKEY 3Department of Thoracic Surgery, Süleyman Demirel University, Faculty of Medicine, ISPARTA, TURKEY |
Keywords:
Lung, Carcinosarcoma |
Pulmonary carcinosarcoma, belonging to sarcomatoid carcinomas,
is a quite rare tumor that contains both malignant epithelial and
mesenchymal elements. This tumor has different phenotypic
characteristics and clinical course compared to non-small cell lung
tumors. A case diagnosed as carcinosarcoma is presented and its
clinical and pathological features and the differential diagnosis are
discussed. The case was a 74-year-old male admitted with shortness
of breath and cough. The chest x-ray showed a left lung mass and
a bronchoscopic examination was performed. Histopathological
examination of the bronchoscopic biopsy showed necrosis and a
malignant tumor consisting of diffuse infiltrative anaplastic cells.
Surgery was performed and the case was diagnosed as carcinosarcoma
in the resection material. Pulmonary carcinosarcoma is a rare lung
tumor. Determination of tumoral cells and performing advanced
investigations in resection material seem to be relatively easier than
in small biopsies. However, this type of tumor can be encountered in
small biopsy materials as in the presented case and should be kept in
mind in relation to the differential diagnosis as small tissues can have
only one, particularly mesenchymal, tumoral component.
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