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2011, Volume 27, Number 1, Page(s) 087-090     
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DOI: 10.5146/tjpath.2010.01053
Childhood Intracranial Germinoma with Granulomatous Reaction
Gülen GÜLNİFLİOĞLU1, Mehtat ÜNLÜ1, Nurullah YÜCEER2, Erdener ÖZER1
1Departments of Pathology, Dokuz Eylül University, Faculty of Medicine, İZMİR, TURKEY
2Departments of Neurosurgery, Dokuz Eylül University, Faculty of Medicine, İZMİR, TURKEY
Keywords: Brain, Germ cell neoplasms, Germinoma, Granuloma, Corpus callosum

Central nervous system tumors are the second most common type of childhood cancer in Turkey. Germinomas constitute two thirds of intracranial germ cell tumors. The granulomatous inflammation occurring around germinomas can cause histological diagnostic difficulty. We present a 12-year-old girl with a diagnosis of germinoma in the corpus callosum associated with granulomatous reaction to emphasize the diagnostic challenge which may occur during stereotactic biopsy interpretation or intraoperative consultation.

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