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2011, Volume 27, Number 1, Page(s) 087-090
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DOI: 10.5146/tjpath.2010.01053 |
Childhood Intracranial Germinoma with Granulomatous Reaction |
Gülen GÜLNİFLİOĞLU1, Mehtat ÜNLÜ1, Nurullah YÜCEER2, Erdener ÖZER1 |
1Departments of Pathology, Dokuz Eylül University, Faculty of Medicine, İZMİR, TURKEY
2Departments of Neurosurgery, Dokuz Eylül University, Faculty of Medicine, İZMİR, TURKEY |
Keywords:
Brain, Germ cell neoplasms, Germinoma, Granuloma, Corpus callosum |
Central nervous system tumors are the second most common type
of childhood cancer in Turkey. Germinomas constitute two thirds
of intracranial germ cell tumors. The granulomatous inflammation
occurring around germinomas can cause histological diagnostic
difficulty. We present a 12-year-old girl with a diagnosis of germinoma
in the corpus callosum associated with granulomatous reaction
to emphasize the diagnostic challenge which may occur during
stereotactic biopsy interpretation or intraoperative consultation.
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