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2011, Volume 27, Number 3, Page(s) 210-214
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DOI: 10.5146/tjpath.2011.01077 |
Multicystic Dysplastic Kidney: Four-Year Evaluation |
Berna AYTAÇ1, İbrahim ŞEHİTOĞLU1, Hakan VURUSKAN2 |
1Department of Pathology Uludağ University, Faculty of Medicine, BURSA, TURKEY 2Department of Urology, Uludağ University, Faculty of Medicine, BURSA, TURKEY |
Keywords:
Multicystic dysplastic kidney, Multicystic renal dysplasia |
Objective: Multicystic dysplastic kidney is a relatively common
developmental abnormality in infants and children. Additional
abnormalities like vesicoureteral reflux, ureteropelvic junction
obstruction, and ureterovesical junction obstruction may accompany
multicystic dysplastic kidney. In this article, we reviewed the
pathogenesis, diagnosis, associated urinary tract anomalies and
results of management of multicystic dysplastic kidney in the light
of the literature.
Material and Method: We retrospectively assessed 20 children with
unilateral multicystic dysplastic kidney between January 2005 and
December 2009. Mean duration of follow-up was 35 ± 8.7 months. All
children with multicystic dysplastic kidney underwent nephrectomy.
Patient characteristics, the pathology findings, associated urinary
tract anomalies and results of management were reviewed.
Results: Abdominal ultrasound, voiding cystourethrography and
renal scintigraphy revealed vesicoureteral reflux in 3 (15%) children,
ureteropelvic junction obstruction in 3 (15%) children, and a duplex
system in the contralateral kidney in 1 (5%) child. Blood pressure
values, serum urea, creatinine and urinalysis were within normal
range in all children during follow-up.
Conclusion: A conservative approach to children with multicystic
dysplastic kidney has been advocated, but surgical removal is also
another management modality on the basis of risk of hypertension,
mass effect, potential for malignant change, and cost of repeated
ultrasound examination.
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