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2019, Volume 35, Number 3, Page(s) 254-257
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DOI: 10.5146/tjpath.2017.01408 |
Follicular Dendritic Cell Sarcoma of the Larynx: Apropos a Rare Case with Review of the Literature |
Ayushi SAHAY, Munita BAL , Asawari PATIL, Shubhada KANE, Prathamesh PAI |
Department of Pathology, Tata Memorial Center, MUMBAI, MAHARASHTRA, INDIA |
Keywords:
Follicular dendritic cell sarcoma, Larynx neoplasm, Podoplanin, Immunohistochemistry |
Extranodal follicular dendritic cell sarcomas are extremely rare neoplasms included under the hematolymphoid and dendritic group of
neoplasms. Histologically, fascicular, whorled spindle cells with sprinkled lymphocytes are typical; however higher grade epithelioid morphology
seen in a subset makes diagnosis of follicular dendritic cell sarcoma challenging. Rarity of occurrence, a wide histologic spectrum and a long list
of differential diagnostic entities render follicular dendritic cell sarcoma an under-recognized entity susceptible to diagnostic pitfalls. Application
of a judicious panel of immunohistochemical markers is imperative to avoid errors in diagnosis and patient management. We report here an
extremely rare case of follicular dendritic cell sarcoma of the larynx- a hitherto unreported site.
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