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2013, Volume 29, Number 3, Page(s) 244-245
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“Pure” Primary Large Cell Neuroendocrine Carcinoma of the Urinary Bladder
Ayşegül SARI
İzmir Atatürk Eğitim ve Araştırma Hastanesi, Katip Çelebi Üniversitesi, Tıp Fakültesi, Patoloji Bölümü, İZMİR, TURKEY
Introduction
Author's Reply:
We thank the author for his interest and valuable comments on our recent publication1. In our article, we investigated all the English literature to the best of our knowledge, and summarized all the reported cases of large cell neuroendocrine carcinoma of the urinary bladder in one table.

Our paper has been accepted for publication in the Turkish Journal of Pathology on April 20, 2011 and published in the 2nd issue (May) of 2013, which is approximately 2 years aft er the acceptance date. Therefore newly published cases of large cell neuroendocrine carcinoma (LCNEC) of the bladder in this time period of two years did not appear on the review table of our article. However aft er careful investigation of the English literature, we noticed that articles published by Bertaccini A et al.2 in 2008 and Lee W et al.3 in 2009 were not presented in our table.

We preferred to include and specify both pure and mixed forms of this tumor in our table in order to better understand the behaviour of this very rare tumor as many of these cases were reported to have mixed histology.

Yours sincerely

Ayşegül SARI

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  • Introduction
  • References
  • References

    1) Sari A, Ermete M, Sadullahoğlu C, Bal K, Bolükbaşi A: Large cell neuroendocrine carcinoma of urinary bladder; case presentation. Turk Patoloji Derg 2013, 29:138-142

    2) Bertaccini A, Marchiori D, Cricca A, Garofalo M, Giovannini C, Manferrari F, Gerace TG, Pernetti R, Martorana G: Neuroendocrine carcinoma of the urinary bladder: Case report and review of the literature. Anticancer Res 2008, 28(2B): 1369-1372

    3) Lee WJ, Kim CH, Chang SE, Lee MW, Choi JH, Moon KC, Koh JK: Cutaneous metastasis from large-cell neuroendocrine carcinoma of the urinary bladder expressing CK20 and TTF-1. Am J Dermatopathol 2009, 31:166-169

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  • Introduction
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