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2000, Volume 16, Number 3-4, Page(s) 067-070
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EPITHELIOID SARCOMA (CLINICOPATHOLOGICAL AND IMMUNOHISTOCHEMICAL FEATURES IN 5 CASES)
Bilge BİLGİÇ, Misten DEMİRYONT, Harzem ÖZGER, Neşe KARADAĞ, Türker ÖZKAN
İstanbul Üniversitesi İstanbul Tıp Fakültesi Patoloji Anabilim Dalı, İstanbul Üniversitesi İstanbul Tıp Fakültesi Ortopedi ve Travmatoloji Anabilim Dalı, İnönü Üniversitesi Turgut Özal Tıp Merkezi Patoloji Anabilim Dalı, İstanbul Üniversitesi İstanbul Tıp Fakültesi Plastik ve Rekonstrüktif Cerrahi Anabilim Dalı
Abstract
Epithelioid sarcoma is a soft tissue sarcoma of young adults and the most common locations are fingers, hand and forearm. The tumor is often multinodular showing central necrosis. Epithelioid cells with large, eosinophilic cytoplasm and spindle cells are both seen. Epithelial membran antigen (EMA), cytokeratin and vimentin are always positive. The histogenesis of the tumor is debatable. The tumor has a high potential of local recurrence and metastasis and must be treated with radical excision. Five cases of epithelioid sarcoma were presented. One patient was female. The median age was 28. The tumor locations were finger, hand or forearm. Three cases had died with distant metastasis. One patient had local recurrence. One patient was lost for follow-up. Follow-up ranged from 2 - 5.5 years.
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