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2016, Volume 32, Number 3, Page(s) 211-215
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DOI: 10.5146/tjpath.2014.01250 |
Adrenocortical Oncocytic Carcinoma: A Case Report and Review of the Histopathologic Diagnostic Criteria |
Deniz ARIK, Funda CANAZ, Emine DÜNDAR |
Eskişehir Osmangazi Üniversitesi, Tıp Fakültesi, Patoloji Anabilim Dalı, ESKİŞEHİR, TÜRKİYE
Department of Pathology, Eskişehir Osmangazi University, Faculty of Medicine, ESKİŞEHİR, TURKEY |
Keywords:
Adrenal gland neoplasms, Adrenocortical carcinoma, Oxyphil cells |
Oncocytic tumors are rare in the adrenal gland. The histopathological
diagnosis of adrenocortical carcinoma is difficult due to the lack of
precise diagnostic criteria for malignancy. A 44-year-old man was
admitted to our hospital with left flank pain. Radiologically an adrenal
mass was detected. After the excision and histopathologic evaluation
of the mass, a diagnosis of adrenocortical oncocytic carcinoma was
made. At least one of the features of more than 5 mitoses in 50 high
power fields, atypical mitotic figures or venous invasion is required
for the diagnosis of malignancy in adrenocortical tumors. It has been
suggested that tumors that have more than one of the minor criteria
of large size (>10 cm or >200 gr), necrosis, capsular or sinusoidal
invasion, should be evaluated as having uncertain malignant potential.
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